An Ounce Of Prevention Is Worth A Pound Of Cure!

Posts tagged ‘vitamin D’

Vitamin D Could Lower Risk Of Developing Type 2 Diabetes

D Drops Vitamin D

Diabetes symbol

Research scientists at the Helmholtz Zentrum München in Germany have shown that people with the proper supply of vitamin D are at lower risk of developing Type 2 diabetes mellitus. The study, which was conducted in cooperation with the German Diabetes Center and the University of Ulm. The report was published in the scientific journalDiabetes Care.


The researchers collaborated with scientists from the department of Medicine/Cardiology at the University of Ulm and German Diabetes Center in Düsseldorf.


New tests performed on participants of the KORA study have shown that people with a proper supply of vitamin D have a lower risk of developing Type 2 diabetes mellitus, while individuals with lower concentrations of vitamin D in their blood have a higher risk. This effect could be attributable to the anti-inflammatory effect of vitamin D.


The result of the study could have direct consequences for the prevention of this common disease.


“Vitamin D deficiency is relatively widespread due to our modern way of life and the geographical latitude of Germany. In the winter months, in particular, people often do not receive adequate supplies of the vitamin because of the lack of sunlight,” explained researchers from the Institute for Epidemiology II at the Helmholtz Zentrum München.

“If follow-up studies confirm our results, a targeted improvement in the supply of vitamin D to the general public could at the same time reduce the risk of developing diabetes.” The human body can produce vitamin D itself if it has sufficient exposure to sunlight. The UVB radiation in natural daylight splits the precursor of vitamin D, 7-dehydrocholesterol, in the skin and forms provitamin D3. Further vitamin D synthesis occurs in the liver and kidneys.


The supply can be improved by eating certain foods, such as vegetables, fruits, olive oil, omega 3-richfish, eggs and milk

Diabetes Dietary Foodsproducts and by taking vitamin D supplements.
Over six million people in Germany suffer from Type 2 diabetes mellitus, and the number of undiagnosed cases could be equally high or more. Unfortunately, there has been no cure for this common disease. Type 2 diabetes is a disorder of glucose metabolism. It is characterized by a loss of insulin action and a drop in the levels of the hormone produced by the body.


The mechanisms that trigger the disease have not yet been fully clarified. However, it is known that diabetes is caused by a combination of genetic and lifestyle factors. The objective of the Helmholtz Zentrum München is to understand the mechanisms
that cause common diseases and to develop new approaches with regard to their diagnosis, therapy and prevention.


Story Source: Helmholtz Zentrum Muenchen – German Research Centre for EnvironmentalHealth.


Journal Reference: Effect of Serum 25-Hydroxyvitamin D on Risk for Type 2 Diabetes MayBe Partially Mediated by Subclinical Inflammation: Results from the MONICA/KORA
Augsburg study. Diabetes Care, 2011;


Helmholtz Zentrum Muenchen – German Research Centre for Environmental Health (2011, October 4). Vitamin D could lower risk of developing Type 2 diabetes, study suggest.

This article is for informational and educational purposes only; It is not intended to provide medical advice,diagnosis or treatment. Contact your doctor or healthcare professional for medical and nutritional consultation.

Low Vitamin D Levels Linked to Higher Death Risk



Low Levels of Vitamin D May Increase The Risk of Dying From All Causes by 150 %, Suggests a Study With Over 700 Elderly Women.

Women with blood levels of the vitamin lower than 15.3 nanograms per millilitre were more likely to die from causes such as heart disease and cancer, than women with higher levels, according to findings published in Nutrition Research.

“The present findings from this population-based cohort of aging are consistent with the association between low serum and mortality that has been described in the general population,” wrote the researchers from the Johns Hopkins University.

“In addition, a recent meta-analysis suggested that Vitamin D supplementation was associated with decreased mortality,” they added.

The researchers noted that several biologic mechanisms could explain a causal relationship between Vitamin D deficiency and mortality, with the vitamin linked to a range of effects including control of inflammatory compounds, regulating immune health and blood pressure, or reducing arterial hardening.

“The role that Vitamin D plays in different tissues may account for the associations between vitamin D deficiency and cardiovascular disease, cancer, and mortality,” they said.

The general population study used data from 13,331 men and women participating in the Third National Health and Nutritional Examination Survey (NHANES III). The results of the study made headlines around the world when published last year in the Archives of Internal Medicine.

The new study looked at Vitamin D levels in 714 community-dwelling women, aged between 70 and 79 years, participating in the Women’s Health and Aging Studies I and II.

The Johns Hopkins researchers worked in collaboration with scientists from Wake Forest University, National Institute on Aging, University of Pennsylvania, and Columbia University.

Study Details

During 6 years of follow-up, 100 of the 714 women died with data showing that the main causes of death included cardiovascular disease (36 per cent), respiratory disease (18 per cent), cancer (15 per cent), and other causes (27 per cent), state the researchers.

When the researchers divided women into four groups (quartiles) according to their 25(OH)D levels, the proportion of women who died in during those 6 years in each quartile (from lowest to highest) was 19, 13,15, and 8.1 per cent, said the researchers.

Increasing blood levels of Vitamin D were linked to increasing survival rates, with women with the lowest average 25(OH)D levels having “significantly worse survival” than women with the highest average levels of 25(OH)D.

“Controlled clinical trials are needed to determine whether Vitamin D supplementation will improve health outcomes such as cardiovascular disease and mortality in older adults who have insufficient levels of Vitamin D,” concluded the researchers.

Vitamin D refers to two biologically inactive precursors – D3, also known as cholecalciferol, and D2, also known as ergocalciferol. The former, produced in the skin on exposure to UVB radiation (290 to 320 nm), is said to be more bioactive.

While our bodies do manufacture Vitamin D on exposure to sunshine, the levels in some northern countries are so weak during the winter months that our body makes no Vitamin D at all, meaning that dietary supplements and fortified foods are seen by many as the best way to boost intakes of Vitamin D.

In adults, it is said Vitamin D deficiency may precipitate or exacerbate osteopenia, osteoporosis, muscle weakness, fractures, common cancers, autoimmune diseases, infectious diseases and cardiovascular diseases. There is also some evidence that the vitamin may reduce the incidence of several types of cancer and type-1 diabetes.

Source: Nutrition Research Volume 29, 525-530 “Low serum 25-hydroxyvitamin D concentrations are associated with greater all-cause mortality in older community-dwelling women”

This article is for informational and educational purposes only; It is not intended to provide medical advice, diagnosis or treatment. Consult your doctor or healthcare professional.


Tag Cloud