New Tufts research has linked low blood levels of vitamin B6 to markers of inflammation that contribute to heart disease and other chronic conditions.
Researchers analyzed data on 2,229 men and women from the “Framingham Offspring” study. They found that levels of PLP, an indicator of vitamin B6 levels in the blood, correlated with 13 different markers of inflammation.
The same associations weren’t seen with the other B vitamins, suggesting a specific link,
although the observational study couldn’t prove cause and effect.
“Low vitamin B-6 status, based on plasma concentrations of PLP, has been identified
in inflammatory diseases, including cardiovascular disease, rheumatoid arthritis, inflammatory bowel disease, and diabetes,” the researchers noted.
“This study, in combination with past findings, further supports our hypothesis that
inflammation is associated with a functional deficiency of essential vitamin B6.”
Journal of Nutrition